The 39-year-old, a past All-Australian and two-time St Kilda best and fairest, was charged with trafficking large commercial quantities of illicit drugs after detectives searched a Sandringham property on Wednesday morning.

Drugs, including methylamphetamine and 1,4-Butanediol, and a Mercedes Benz were seized in the raid.

Fisher did not appear when his case was briefly mentioned in Melbourne Magistrates Court on Wednesday evening, with his lawyer declaring he preferred to remain in custody.

The matter has been adjourned until August 10.

It comes after WA Police seized a parcel on April 20 with $129,000 inside that was allegedly meant to be delivered to a Melbourne address.

Another parcel allegedly from Melbourne, containing about one kilogram of methylamphetamine and 84 grams of cocaine concealed inside a kitchen appliance, was intercepted by WA police on the same day.

Police will allege that drugs of dependence were regularly being concealed in white goods and sent from Melbourne to Perth.

Detective Inspector Craig Darlow of the Trident Taskforce said the bust was a "remarkable result".

"There may be a perception drugs can be easily concealed, however we have seen time and time again, the ability of police to detect and seize these substances," he said in a statement.

"This is a warning that regardless of where you are or where how you operate, we will target those involved in the manufacture and trafficking of illicit drugs and hold them to account."

Australian Associated Press